Cancer Knowledge Base Developer

Published date Posted on Indeed on Jan 14, 2022 (9 d ago)
Cancer Knowledge Base Developer
Location: Remote
Travel: N/A

Who We Are
M2GEN is seeking people who are passionate about making a difference in the lives of cancer patients and who want to join a science-focused and purpose-driven team. In order to be a leader in creating and delivering health informatics solutions through evidence-based approaches to predict and meet the needs of cancer patients, we need an all-star team. Be part of the cure by joining M2GEN's team and impacting the future of cancer care.

We are a fast‑growing company and if you are interested in data, science, or medicine and want to help us make precision medicine a reality, review our current open positions and apply today.

What You’ll Do
M2Gen is hiring a Cancer Knowledge Base Developer who will be responsible for development of a comprehensive knowledge base that incorporates all critical data for cancer genomics and genetics, cancer cell evolution, disease progression and response to treatments. Specific duties include evaluating approaches, data models and platforms for a cancer knowledge base, integrating internal and external molecular and clinical datasets, and enabling functionality that describe and predict cancer response and evolution under various treatments/conditions.

The Cancer Knowledge Base Developer works as part of the Science and Innovation group, as well as collaboratively with the M2GEN Engineering and Clinical Data teams, and externally with service and technology vendors to coordinate key operational aspects of deriving clinical significance from tumor/normal whole exome and tumor-only RNA sequencing assays. As part of the Science and Innovation - Data Integration and Platform Informatics team, you will be responsible for evaluating disparate databases and developing an aggregate knowledge base to inform on the function of somatic mutations and their therapeutic implications (if applicable). This position will directly contribute toward the evolution of our infrastructure that enables insight into cancer genes and their function, genetic alternations, frequencies and outcomes, therapeutic implications, and FDA-approved drugs or investigational agents in clinical trials.

Who You Are
The candidate should be experienced in medical informatics (oncology specific), database management, and data analysis using R.
  • A clinical and molecular data analyst committed to applying programming and database skills for research discovery and clinical benefit
  • Interested in aggregating large clinic-genomic datasets and the development of transformative inferences
  • An experienced biostatistician, data wrangler and database programmer in cancer medical informatics
  • Effective communicator with experience in result/conclusion visualizations, presentations, reports using business intelligence tools, such as: Power BI or Qlik
  • Familiar with source control systems, as well as software testing methodologies and concepts
  • A person who enjoys working in a team, is self-motivated, can manage multiple tasks simultaneously, and can solve problems independently

What You Need
  • Masters or PhD in Public Health, Epidemiology, Biostatistics, Computer Science, Bioinformatics, or other applied science with knowledge base development experience
  • Experience with SQL, ETL data synchronization
  • Experience with SAS, Tableau, Power BI, and continuous development/deployment tools, such as: JIRA/Confluence or MS DevOps
  • Experience with clinical/hospital electronic medical record (EMR) systems, such as: Epic, Allscripts
  • Advanced knowledge of scripting and programming languages such as Python and R
  • Ability to apply troubleshooting techniques to resolve complex, cross functional issues
  • Strong organizational skills, attention to detail and accuracy
  • Excellent written and verbal communication skills to interact with both clinical researchers and IT professionals
M2Gen, in accordance with Equal Employment Opportunity Policy GP-08, does not discriminate on the basis of race, color, religion, sex, sexual orientation, age national origin, marital status, citizenship, physical or mental disability, veteran status, or any other protected trait. Additionally, M2Gen will consider reasonable accommodations whenever necessary to provide equal employment opportunities to otherwise qualified individuals with a disability. The above job posting is intended to describe the general nature and level of work being performed by the person(s) assigned to this job. The above is not intended to be an all-exhaustive list of responsibilities and duties required and may include other duties as assigned. M2Gen reserves the right to modify, add, delete, or substitute certain responsibilities and duties at its sole discretion.

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